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Anatomy of a Scientific Discovery – Jeff Goldberg

READ GREEN WITH E-BOOKS

Anatomy of a Scientific Discovery
The Race to Find the Body’s Own Morphine
Jeff Goldberg

Genre: Life Sciences

Price: $2.99

Publish Date: September 1, 2013

Publisher: Skyhorse Publishing

Seller: OpenRoad Integrated Media, LLC


The “fascinating” story of the global scientific race to discover and unlock the power of endorphins—the body’s own morphine ( The New Yorker ).   In 1973, scientists John Hughes and Hans Kosterlitz were studying pig brains in an underfunded laboratory in Aberdeen, Sweden. During their research, the duo discovered a non-addictive narcotic chemical. What if they could find a similar chemical in humans? If human brains also had this chemical and they could somehow isolate it, perhaps Hughes and Kosterlitz could find a way to help the world begin to heal itself. Their work would lead them to discover endorphins, the body’s own natural morphine and the chemical that makes it possible to feel both pain and pleasure.   Their findings made Hughes and Kosterlitz overnight celebrities. Soon, scientists all over the world were rushing to study the human brain and its endorphins. In a few years, scientists would use the team’s initial research to link endorphins to drug addiction, runner’s high, appetite control, sexual response, and mental illnesses such as depression and schizophrenia.   In Anatomy of a Scientific Discovery , Jeff Goldberg describes Hughes and Kosterlitz’s lives before, during, and after their historic and scientific breakthrough. He also reveals the brutal competition between drug companies as they raced to find a way to cash in on this monumental discovery.  

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Anatomy of a Scientific Discovery – Jeff Goldberg

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Donald Trump and the True Meaning of "I Disavow"

Mother Jones

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I’ve now written my quota of one non-Trump post this morning, and surely that’s enough? So let’s move on. I’m fascinated to see that Joe Weisenthal picked up on something that I noticed too during Trump’s late-night press conference on Tuesday:

Here’s what happened. A reporter asked Trump once again to comment on the David Duke/KKK endorsement, and Trump whined that he had already written a Facebook post and a tweet and, really, just how many times was he supposed to disavow the guy? But as Weisenthal points out, Trump repeatedly said “I disavow, I disavow, I disavow,” without ever mentioning who he was disavowing. And since the reporters weren’t given mics, you really couldn’t hear what the question was about. You’d only know if you’ve been following this controversy.

I don’t think this was a mistake. Trump has done it too many times. On Facebook, on Twitter, on Good Morning America, and then again last night. His ritualistic phrase is “I disavow” without providing a clear, simple soundbite about who or what he’s disavowing. Nor does he ever say anything more in the way of condemnation. His Twitter and Facebook posts, for example, had merely this terse comment: “As I stated at the press conference on Friday regarding David Duke- I disavow.”

It’s pretty clear what’s going on here. Technically, Trump is in the clear. He has disavowed David Duke. But there is no soundbite or video snippet that shows him clearly criticizing either Duke or the KKK or white supremacist groups in general. And as Trump knows better than anyone, it’s audio and video excerpts that really matter. That’s what people see, not brief Twitter or Facebook posts.

Trump now has the best of all worlds. He can truthfully say that he’s repeatedly denounced David Duke. He can mock the media for unfairly making a big deal out of it. But for his less savory supporters, there’s no video of him clearly and unequivocally condemning the Duke or the KKK—and they understand perfectly well what this means. They’re old hands at the wink and the nod.

If it were anyone else, I’d say this was all carefully calculated. But Trump has such an instinctive grasp of TV that I wouldn’t be surprised if this just came naturally to him without any real thought. He is truly a master of the modern media era.

UPDATE: This is fascinating. One minute after publishing this, I wandered over to The Corner and read a Jonah Goldberg post making exactly the same point I did. Goldberg doesn’t think Trump’s phrasing is an accident either:

It is obvious to me that Trump didn’t want to denounce David Duke and the Klan in the Jake Tapper interview. The “bad earpiece” explanation is a transparent lie….And when Tapper mentioned the KKK, Trump still didn’t say, “Wait a second . . . ” and rip into the Klan. The question is, Why?

….Denouncing the Klan should be easy. You shouldn’t have to think about it….The one thing you shouldn’t do is sound like you’re reluctant to condemn the Klan(!) or that you’re dog-whistling that you don’t really mean it when you do. Yet when you watch the Tapper interview, it becomes clear what is really going on: He think condemning the Klan will hurt him with conservatives or southerners or both….In other words, the issue isn’t that conservative opponents of Trump think he’s a Klan supporting racist, it’s that Trump thinks many of his conservative supporters are. And that’s just one reason I don’t want this guy speaking for me.

Yep. And when was the last time Goldberg and I agreed about something? It just goes to show that Trump really does bring people together.

Originally posted here: 

Donald Trump and the True Meaning of "I Disavow"

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Let’s Not Rewrite History on Gun Violence

Mother Jones

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“This is something we should politicize,” President Obama said last week after the gun massacre in Oregon. “It is relevant to our common life together, to the body politic.” Jonah Goldberg is annoyed that Obama said this even though he’s routinely spoken out against politicizing issues in the past. “He’s not about to try building consensus on gun violence among people of good faith,” Goldberg says. Then this:

Obama’s comments on Thursday highlighted the problem with his approach to politics. He would rather go for everything he wants and get nothing, but keep the political issue, than make progress on common ground.

Virtually none of the proposals on his gun-control wish list — more comprehensive federal background checks, closing the gun show “loophole,” etc. — would help bring down the homicide rate….Typically, mass killers don’t buy guns at gun shows. And a CNN analysis found that a comprehensive background check system wouldn’t have prevented any of the “routine” killing sprees Obama referred to, save one.

….After the Sandy Hook slaughter, there was a bipartisan consensus that more needed to be done on the mental health side. But Obama, fresh off reelection, rejected a piecemeal approach, largely preferring to go for a “comprehensive” solution. He ended up with nothing at all.

Um, what? Shortly after Sandy Hook, Joe Biden released the final report of his task force on gun violence. It contained recommendations in four areas, one of which was increased access to mental health services. Several bipartisan bills that targeted mental health did indeed get introduced, and I believe Obama supported all of them. So why didn’t they pass? That’s always hard to say, but the best guess is that it’s because they all cost money, and Republicans were unwilling to vote for increased spending. So they died. Obama’s preference for a “comprehensive” approach had nothing to do with it.

Beyond that, sure, Obama wanted comprehensive legislation. But in the end, this got whittled down to one thing: a bipartisan bill mandating universal background checks. It was watered down repeatedly, and was about as weak as possible by the time it finally got a vote. Despite massive public support, even from gun owners, it failed after an enormous effort to reach out to all those people of good faith Goldberg talks about. I think you can guess who voted against it.1

1It was 41 Republicans and 5 Democrats, in case you’ve forgotten.

Original source:

Let’s Not Rewrite History on Gun Violence

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Sorry, Conservatives: You Deserve Donald Trump

Mother Jones

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From Jonah Goldberg, in an epic lament about the trumpenproletariat’s crush on Donald Trump and the willingness of mainstream conservatives to pander to it:

Every principle used to defend Trump is subjective, graded on a curve. Trump is like a cat trained to piss in a human toilet. It’s amazing! It’s remarkable! Yes, yes, it is: for a cat. But we don’t judge humans by the same standard.

I think this is unfair to cats who learn to piss in the toilet. At least that’s a useful skill, and at least they don’t spend all their free time bragging about it. Still, fair point.

On a related note, I continue to be impressed at the number of conservatives who are aghast not at Trump per se, but at the fact that the conservative base is so enamored of him. Most conservative support of Trump is “venting and resentment pretending to be some kind of higher argument,” Goldberg says. And then: “I am tempted to believe that Donald Trump’s biggest fans are not to be relied upon in the conservative cause.” Ya think?

But surely Goldberg understands that this is the right-wing base that he and his colleagues have built? I don’t expect any conservative writer to acknowledge this in public, but surely in the occasional dark night of the soul they understand what they’ve done? For years they’ve supported the worst know-nothing bombast of Drudge and Limbaugh, the casual reality distortion of Fox News, and the resentment-based appeals of people like Newt Gingrich and Sarah Palin. And they’ve turned a blind eye to even worse: birthers, Agenda 21 lunacy, Cliven Bundy’s army, and much, much more. It was handy at the time, and helped win a few elections. But now the outrage-based mob they’ve nurtured has come back to haunt them—and unsurprisingly, it turns out not to care all that much about the debating-hall nuances of Edmund Burke and Russell Kirk. They just want to kick out the wetbacks and get back at those smug liberals who make fun of them.

Live by the sword, die by the sword. But if you want to survive, you’d better at least understand that once forged, a sword can be wielded by anyone strong enough to grab it. You might not like it when your army decides to follow, but you’re the one who taught them to follow the shiny object without worrying too much about whose hand is on the hilt, aren’t you?

Originally from: 

Sorry, Conservatives: You Deserve Donald Trump

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Detroit Just Had the Single Largest Tax Foreclosure in American History

Mother Jones

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This story first appeared on the TomDispatch website.

Unlike so many industrial innovations, the revolving door was not developed in Detroit. It took its first spin in Philadelphia in 1888, the brainchild of Theophilus Van Kannel, the soon-to-be founder of the Van Kannel Revolving Door Company. Its purpose was twofold: to better insulate buildings from the cold and to allow greater numbers of people easier entry at any given time.

On March 31st at the Wayne Country Treasurer’s Office, that Victorian-era invention was accomplishing neither objective. Then again, no door in the history of architecture—rotating or otherwise—could have accommodated the latest perversity Detroit officials were inflicting on city residents: the potential eviction of tens of thousands, possibly as many as 100,000 people, all at precisely the same time.

Little wonder that it seemed as if everyone was getting stuck in the rotating doors of that Wayne County office building on the last day residents could pay their past-due property taxes or enter a payment plan to do so. Those who didn’t, the city warned, would lose their homes to tax foreclosure, the process by which a local government repossesses a house because of unpaid property taxes.

Continue Reading »

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Detroit Just Had the Single Largest Tax Foreclosure in American History

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Is Obama Trolling Republicans Over Immigration?

Mother Jones

Jonah Goldberg is unhappy with President Obama’s immigration order, but he’s not steaming mad about it. And I think this allows him to see some things a little more clearly than his fellow conservatives:

Maybe President Obama is just trolling?

….As Robert Litan of the Brookings Institution notes, Obama “could’ve done all this quietly, without making any announcement whatsoever.” After all, Obama has unilaterally reinterpreted and rewritten the law without nationally televised addresses before. But doing that wouldn’t let him pander to Latinos and, more important, that wouldn’t achieve his real goal: enraging Republicans.

As policy, King Obama’s edict is a mess, which may explain why Latinos are underwhelmed by it, according to the polls. But that’s not the yardstick Obama cares about most. The real goal is twofold: Cement Latinos into the Democratic coalition and force Republicans to overreact. He can’t achieve the first if he doesn’t succeed with the second. It remains to be seen if the Republicans will let themselves be trolled into helping him.

Don’t get me wrong. I’m pretty certain that Obama did what he did because he really believes it’s the right thing to do. Goldberg just isn’t able to acknowledge that and retain his conservative cred. Still, somewhere in the Oval Office there was someone writing down pros and cons on a napkin, and I’ll bet that enraging the GOP caucus and wrecking their legislative agenda made it onto the list of pros. So far, it looks like it’s probably working. But if Republicans are smart, they’ll figure out some way to follow Goldberg’s advice and rein in their worst impulses. If they go nuts, they’re just playing into Obama’s hands.

See original article here – 

Is Obama Trolling Republicans Over Immigration?

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Yet Another IRS Scandal That Isn’t

Mother Jones

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Jonah Goldberg is outraged that there continues to be no outrage over the endless IRS “scandal.” Most of his column is the usual collection of misleading innuendo, but there is one new item: the IRS’s claim that Lois Lerner’s computer crashed in 2011 and thousands of her emails were lost. That does sound pretty fishy:

So now the IRS claims that a computer crash has irrevocably erased pertinent emails (an excuse I will remember when I am audited). National Review’s John Fund reports that the IRS’ manual says backups must exist. If emails — which exist on servers, clouds and elsewhere — can be destroyed this way, someone should tell the NSA that there’s a cheaper way to encrypt data.

Far be it from me to doubt the word of John Fund, but perhaps Goldberg should instead have read the Washington Post yesterday. The explanation for the crash, perhaps surprisingly, turns out to sound pretty plausible. Basically, the IRS keeps six months worth of email backups on tape, so when congressional investigators started asking for email records in mid-2013, backups were available only through late 2012. Lerner’s computer crashed in mid-2011, so everything prior to that was lost because it existed only in local files on her PC. The IRS has since tried to recover Lerner’s emails from the PCs of people she sent emails to, but that was only partially successful.

Nothing here sets off alarm bells to me. The key question, I think, is whether the IRS has contemporaneous documents showing that Lerner’s computer crashed in 2011 and attempts to recover her hard drive failed. And they do. This is well before the scandal broke, so it would take a pretty Herculean brand of conspiracy theorizing to imagine that this was somehow related to the scandal. Either Lerner deliberately crashed her hard drive because she suspected her actions might prompt an investigation two years later, or else the IRS has faked a bunch of emails from 2011 between Lerner and the IT team trying to recover her hard drive.

There’s also, as Steve Benen points out, the fact that Congress is mostly concerned with Lerner’s behavior in the election year of 2012. If the IRS were involved in a cover-up, faking a hard drive crash that destroyed emails from 2010 and 2011 is a pretty incompetent way of doing it.

So, anyway, that’s where the outrage is. Most of us concluded long ago that regardless of whether IRS policies were correct, the evidence pretty strongly suggests that they were bipartisan, targeting political groups on both left and right. There’s just no scandal there. At most there’s bad judgment, and probably not even that. Likewise, Lerner’s hard drive crash might turn out to be a scandal, but so far it sure doesn’t look like one.

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Yet Another IRS Scandal That Isn’t

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Quote of the Day: The War Party Is Working Hard to Make Iran Look Like a Victim

Mother Jones

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Jeffrey Goldberg:

It would be quite an achievement to allow Iran, the world’s foremost state sponsor of terrorism, to play the role of injured party in this drama. But the Senate is poised to do just that.

Goldberg is talking about the possibility that the Senate will pass a sanctions bill against Iran just as the Iranians have finally agreed to come to the table and negotiate an agreement to dismantle their nuclear program. As Goldberg says, this makes sense only if you’re hellbent on a military strike against Iran and flatly eager to sabotage anything that might lead to a peaceful settlement. It’s hard to believe that this is the position of the entire Republican Party as well as a pretty good chunk of the Democratic Party, but apparently it is. It’s especially hard to believe given the realities of what it would accomplish:

While it could set back (though not destroy) Iran’s nuclear program, it could also lead to the complete collapse of whatever sanctions remained in place. In addition, it could unify the Iranian people behind their country’s unelected leader, Ayatollah Ali Khamenei — a particularly perverse outcome. And in some ways, an attack would justify Iran’s paranoia and pursuit of nuclear weapons: After all, the regime could somewhat plausibly argue, post-attack, that it needs to defend itself against further aggression. A military campaign should be considered only when everything else has failed, and Iran is at the very cusp of gaining a deliverable nuclear weapon.

….So why support negotiations? First: They just might work. I haven’t met many experts who put the chance of success at zero. Second: If the U.S. decides one day that it must destroy Iran’s nuclear facilities, it must do so with broad international support. The only way to build that support is to absolutely exhaust all other options. Which means pursuing, in a time-limited, sober-minded, but earnest and assiduous way, a peaceful settlement.

This is exactly right. As it happens, I doubt that we’ll be able to reach a final deal with the Iranians. In the end, I think Iran’s hawks have too much influence and just won’t be willing to give up their nuclear ambitions. What we’ll do then is anyone’s guess. But as Goldberg says, even if you’re a hawk who favors a military strike, surely you’re also in favor of demonstrating to the world that we did everything humanly possible to avoid it. What possible reason could you have for feeling differently?

From: 

Quote of the Day: The War Party Is Working Hard to Make Iran Look Like a Victim

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